![]() I stopped all medication and now seem to be gradually recovering, but the rash persists. “I have extreme fatigue (like sleeping sickness). I also experienced muscular pains, tinnitus in both ears and diminished hearing. I suddenly developed an intense red spotty body rash (like measles). “I have been on 5 mg of amlodipine plus statins for two years. Here are just a few comments: Gary in New Zealand is suffering: Skin Reactions:Īlthough there is mention of “allergic reaction,” “pruritis” (also known as itching) and “rash,” these are not perceived as common or terribly worrisome. However, some people find its common side effects such as fluid retention (edema), dizziness, flushing, palpitations, fatigue and digestive distress are hard to handle. You will find it under the Health eGuides tab.Īmlodipine has been shown to reduce the likelihood of a heart attack or stroke ( Cardiology and Therapy, Dec. In addition to the pros and cons of various medications, this online resource discusses non-drug approaches. To help you with that conversation, you may find our eGuide to Blood Pressure Solutions helpful. Perhaps it is time for your doctor to consider a different type of blood pressure medicine for you. The official prescribing information lists “rhinitis” (runny nose) as rare, but it has been reported. In fact, palpitations are fairly common, especially among women. Your symptoms could certainly be side effects of your medication. I take Zyrtec and use nasal spray daily with no relief.Ī. Are these side effects of the medicine? My doctor thinks the palpitations are due to anxiety. I’m now experiencing heart palpitations and an annoying post-nasal drip. My doctor recently doubled my amlodipine dose because my blood pressure was still too high. Palpitations and Post-Nasal Drip: A reader recently shared these problems with amlodipine: But judging from our comment section, many people do experience some of these so-called rare side effects. It is unlikely that patients would be told about anything that affects less than 1%. After all, less than 1% seems almost trivial. But few health professionals take these side effects very seriously. Should someone actually develop one of these seemingly rare side effects, both the company and the FDA can claim that it was listed along with dozens of other symptoms. We also refer to this as the cover your derriere section. The FDA states that “a causal relationship is uncertain.” In other words, these are adverse drug reactions that are supposed to affect fewer than 1% of patients. It is what we refer to as the “ LESS THAN 1%” rate. The FDA has another category for side effects. Dizziness, flushing, headache, sleepiness, fatigue and heart palpitations are also listed, but are not considered common complications of the drug. Dig a little deeper, though, and you will see that over 10% of patients taking 10 mg daily develop edema or fluid retention. That makes it seem as if Norvasc is super safe. In controlled clinical trials directly comparing NORVASC (N=1730) at doses up to 10 mg to placebo (N=1250), discontinuation of NORVASC due to adverse reactions was required in only about 1.5% of patients and was not significantly different from placebo (about 1%).” Most adverse reactions reported during therapy with NORVASC were of mild or moderate severity. In general, treatment with NORVASC was well-tolerated at doses up to 10 mg daily. “NORVASC has been evaluated for safety in more than 11,000 patients in U.S. When you read the prescribing information for Norvasc you learn that Are there any downsides to this drug? The FDA’s Official Info: What this means is that many patients are taking amlodipine and may not even realize it. There is even a drug combo that combines the cholesterol-lowering drug atorvastatin with amlodipine. These combination products are designed to lower blood pressure more effectively than amlodipine alone. The brand name is Lotrel.Īmlodipine plus valsartan is called Exforge There is, for example, amlodipine plus an ACE inhibitor called benazepril. Drug Combinations containing Amlodipine:Īlthough this calcium antagonist is most frequently prescribed as a single pill, increasingly it is combined with other drugs. At last count, over 16 million Americans swallow a pill containing amlodipine every day. This helps dilate blood vessels in the heart and throughout the body.Īmlodipine is perceived by many health professionals as a highly effective, low-risk medication. This calcium channel blocker lowers blood pressure in part by interfering with the flow of calcium into artery walls. For reasons that remain somewhat mysterious to us, amlodipine ( Norvasc) is one of the most popular blood pressure medications in the pharmacy.
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